Pharmaceutical Care Acne Treatment
GD Usenko, IA Zupanets, NV Bezditko specialized dermatological clinic of the Central Hospital of the Ministry of Interior of Ukraine, Ukrainian National Academy of Pharmacy
Acne vulgaris (acne) are found in 80% of the population in the second and third decade of life and more than 90% of adolescents. Clinically significant and require acne treatment affect about 20-25% of the population aged between 12 and 25 years. For the age group of 17 years http://jualobatjerawat.net, the incidence of facial acne is 86.1%. Severe cystic acne occurs in 5 per 1,000 inhabitants aged 18-31 years. Boys are more common and more severe acne than in girls.
The prevalence of severe acne in males than females increases with age.
Although acne is not a serious threat to life or disability of the patient, a cosmetic defect has on many people, especially teenagers, a depressing effect, it contributes to the development of depression, reduces the quality of life.
If you have acne, most of the patients are treated or start the treatment by own account, which makes it particularly relevant pharmaceutical care when using drugs for the treatment of acne.
Acne vulgaris – a chronic inflammatory disease of the sebaceous glands and hair follicles, is more common in teens and people of reproductive age.
Recently, instead of the term “common acne” introduced the term “acne”, which underlines the fact that as a teenager the appearance of acne reflects the change of the whole body, and not a local defect in the skin.
The main factors that are important in the genesis and development of acne:
Genetic predisposition – the number, the size of the sebaceous glands and their sensitivity to the level of androgens (male sex hormones);
increased secretion of androgens during puberty, which promotes the overproduction of sebum;
Activities activation flora saprophytes sebaceous follicles (Propionibacterium acne);
the development of inflammatory reactions in the region of the hair follicle on the background hydrolysis of sebum and multiplication therein P. acnes;
follicular hyperkeratosis (excessive growth of the epithelial cells of the hair follicle, leading to a blockade of the epithelial cells of the sebaceous gland horny scales).
Factors contributing to the formation of acne:
hormonal changes in the body during puberty (increase the level of male sex hormones);
Hormonal changes in women during the premenstrual period (sometimes – during pregnancy);
mechanical factors: habit hand propping his chin, keep your chin up the phone, wearing hats and tight collared shirts buttoned tight, which leads to excessive sweating;